A Reflection on the Types of COVID-19 Vaccines with Emphasis on the Side Effects of Vaccines; A Review


1 Pharmacist, School of Pharmacy, Mashhad University of Medical Sciences Mashhad, Iran.

2 BSN, Bachelor of Science in Nursing, Mashhad University of Medical Sciences, Mashhad, Iran.

3 MD, Pediatrician, Department of Pediatric, Mashhad University of Medical Sciences, Mashhad, Iran.

4 Jiroft University of Medical Sciences, Jiroft, Kerman, Iran.

5 Anesthesiologist, Assistant Professor of Intensive Care, North Khorasan University of Medical Sciences, Bojnord, Iran.



Vaccines save thousands of lives each year. Producing a safe and effective coronavirus vaccine is a huge step forward in global efforts to end the COVID-19 pandemic. COVID-19 vaccines are safe, and getting vaccinated will help protect people against developing severe COVID-19 disease and dying from it. Side effects usually occur within the first few days of getting a vaccine. Since the first mass vaccination program started in early December 2020, hundreds of millions of vaccine doses have been administered. Like any vaccine, COVID-19 vaccines can cause side effects, most of which are mild or moderate and go away within a few days on their own. As shown in the results of clinical trials, more serious or long-lasting side effects are possible. Vaccines are continually monitored to detect adverse effects. Reported side effects of COVID-19 vaccines have mostly been mild to moderate and have lasted no longer than a few days.
According to the Centers for Disease Control and Prevention (CDC) Trusted Source and World Health Organization (WHO) Trusted Source, common side effects of a COVID-19 vaccine include fever, fatigue, headaches, body aches, chills, and nausea. A person might also experience side effects around the injection site, which is usually the upper arm. These might include swelling, pain, redness, and itchy rash, and other mild forms of irritation. The chances of any of these side effects following vaccination differ according to the specific COVID-19 vaccine. Pfizer-BioNTech, Moderna, and Sputnik V vaccines are more effective in the human population than other vaccines. Novavax vaccine has fewer side effects than Pfizer-BioNTech and Moderna.